Mesenteric artery disease develops over time when the arteries in your body build up plaques or harden, leading to reduced blood flow to and through your intestines. Those with mesenteric artery disease often have hardened or narrowed arteries in other parts of the body too and are at high risk for heart disease.

This condition can lead to discomfort while or after eating, as well as more serious complications, such as blood clots and permanent damage to the intestines.

What are the symptoms of mesenteric ischemia or mesenteric artery disease?

Patients can experience different symptoms depending on the severity of a blood clot or blockage in the mesenteric arteries. Sometimes, symptoms may onset suddenly, and others you may experience regularly. Some of the symptoms include:

  • Severe pain when eating
  • Pain that starts 30 minutes after eating, worsens and then abates after an hour or two
  • Unexplained weight loss
  • Vomiting
  • Dizziness

What are the risk factors for mesenteric artery disease?

Because mesenteric artery disease is caused by a general hardening and build-up of plaque in the arteries, its risk factors mirror those of heart disease. The main contributors to mesenteric artery disease are:

  • Smoking
  • Family history of hardened, narrowed arteries or heart disease
  • High blood pressure and high cholesterol
  • Uncontrolled diabetes
  • Advanced age
  • Lack of exercise

What are the complications of mesenteric ischemia and mesenteric artery disease?

Mesenteric artery disease can cause severe pain during or after eating, which can be a notable complication in and of itself. For some patients, this can lead to significant weight loss and malnutrition.

Developing a clot or total blockage (occlusion) in the mesenteric arteries is among the worst potential complications of mesenteric artery disease. Depending on the size of a blood clot, it may be monitored under the supervision of a vascular surgeon and eventually treated through surgery or a minimally invasive endovascular procedure.

Some blood clots cause a complete blockage (total occlusion) of a mesenteric artery. In those cases, immediate surgery will be required to restore blood flow and prevent organ damage.

Treatment Options for Mesenteric Artery Disease

Lifestyle changes

For any patient who is experiencing a buildup of plaque in their mesenteric arteries, lifestyle changes will help them feel better, head off worse complications down the road and give them better outcomes post-surgery. Adopt a heart-healthy lifestyle by:

  • Quitting smoking.
  • Increasing your intake of fruits and vegetables. Eating a low-cholesterol and low-fat diet. Cutting back your salt intake.
  • If you have diabetes, managing your blood glucose and bringing your A1C down.
  • Exercising daily and moving more in your day-to-day life.
Medication

Your vascular surgeon may recommend medications for a variety of reasons if you are diagnosed with mesenteric artery disease.

  • Treating risk factors: Your vascular surgeon, sometimes in concert with a primary care physician or cardiologist, may recommend medication to control other conditions that can cause or worsen mesenteric artery disease. These might include:
    • Medication to lower high blood pressure or high cholesterol
    • Medication to lower A1C in diabetics
    • Georgia Heart Institute also offers a specialized program for patients who have tried medication previously to treat high blood pressure, high cholesterol, or diabetes, but have been unsuccessful at meeting their goals and heading off complications. Learn more about our Center for Cardiovascular Prevention, Metabolism & Lipids.
  • Direct treatment: A type of medication called vasodilators may be prescribed to help improve blood flow in the narrowed arteries. These drugs target mesenteric artery disease directly by relaxing the arteries. These may be given in pill form or through an in-office injection.
  • Treating for complications: Your vascular surgeon may recommend that you start taking a blood thinner. Individuals with narrowed arteries are at increased risk of blood clots, which can be life-threatening and can cause permanent organ damage.
Minimally invasive procedures

For those who have developed a blood clot that is not an acute emergency or total occlusion, we offer a state-of-the-art endovascular suite to reopen the artery and, if necessary, place a stent.

  • Balloon angioplasty: This procedure is performed by making a small incision in the groin and threading a catheter into an artery. Through this catheter, a tiny balloon is placed into the blocked artery and then inflated to create more space for the blood to flow.
  • Stenting: During this same procedure, our vascular surgeons may also place a small mesh tube called a stent into the artery. This helps hold the artery open long-term so blood can flow to the intestines.
Surgery

In some cases, a minimally invasive endovascular procedure may not be possible. Often, open surgery is needed when a patient has a severe or total blockage of a mesenteric artery. In those cases, our vascular surgeons offer:

  • Arterial bypass surgery: Bypass surgery involves redirecting the flow of blood around a severe blood clot, restoring the artery’s function. The surgeon will either use a synthetic tube or harvest a vein from another part of the body, then connect this new “artery” above and below the blockage in your mesenteric artery, restoring the flow of blood and effectively “bypassing” the blood clot. This surgery is done under general anesthesia, and patients should expect a hospital stay afterward.
  • Endarterectomy: In this surgical procedure, the vascular surgeon will open up the mesenteric artery and remove the plaque directly from the artery.This surgery is done under general anesthesia, and patients should expect a hospital stay afterward.

Why choose Georgia Heart Institute?

Our program brings together the expertise and comprehensive purview of the Vascular Center of Northeast Georgia Physicians Group with the advanced technology available through Northeast Georgia Medical Center and wrap-around services from the cardiologists at Georgia Heart Institute.

Our vascular surgeons develop long-term relationships with our patients to ensure they not only have a successful procedure, but also have a successful recovery and maintain their level of care. Whether you need preventive care, disease management, a minimally invasive procedure or surgery, or rehabilitation, we’re here at every step of your journey.

Receiving Vascular Care at Georgia Heart Institute

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